Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29859446 | 1.00 | KDM4E (0.66) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7813594 | 0.84 | KDM4E (0.52) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11291425 | 0.82 | KDM4E (0.48) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11389359 | 0.81 | ALDH1A1 (0.63) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2384520 | 0.81 | KDM4E (0.53) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9147032 | 0.80 | KDM4E (0.51) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7804238 | 0.80 | KDM4E (0.49) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4065612 | 0.80 | KDM4E (0.72) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29415434 | 0.80 | KDM4E (1.00) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2805779 | 0.80 | KDM4E (1.00) | KDM4ETDP1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4211077-A | — | — | None | — | — | JP | disclosed |
| JP-H04211077-A | OPTICALLY ACTIVE 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE, ITS PRODUCTION AND INTERMEDIATE | KYORIN PHARMACEUT CO LTD | 1992-08-03 | — | — | JP | disclosed |