SCHEMBL7804247

SCHEMBL7804247

CON=CCc1ccccc1COc1ccccc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.43
CDK4 P11802 1/20 0.43
CCND1 P24385 1/20 0.43
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HTR1A P08908 1/20 0.39
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
TDP1 Q9NUW8 4/20 0.38
TSHR P16473 2/20 0.38
MAPK1 P28482 2/20 0.38
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
NISCH Q9Y2I1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8817419 0.81 TAAR1 (0.39) CDK4CCND1NPC1TSHRMAPK1
SCHEMBL22138645 0.80 CDK4 (0.53) RECQLCDK4CCND1NPC1RAB9A
SCHEMBL4103628 0.77 ALDH1A1 (0.49) RECQLCDK4CCND1NPC1RAB9A
SCHEMBL9230957 0.77 CDK4 (0.41) RECQLCDK4CCND1NPC1RAB9A
SCHEMBL3521430 0.75 CDK4 (0.60) CDK4CCND1NPC1RAB9AHTR1A
SCHEMBL9422372 0.74 RECQL (0.47) RECQLCDK4CCND1RXRARXRB
SCHEMBL7995638 0.74 RECQL (0.42) RECQLCDK4CCND1HTR1AADRA1D
SCHEMBL13144446 0.74 ABCB1 (0.60) RECQLCDK4CCND1HTR1AADRA1D
SCHEMBL13794253 0.74 CDK4 (0.51) RECQLCDK4CCND1NPC1RAB9A
Bromide SCHEMBL27650271 0.73 CDK4 (0.58) CDK4CCND1NPC1RAB9AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0749419-B1 OXIME DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 2001-10-24 EP disclosed
EP-0749419-A1 OXIME DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AG (DE) 1996-12-27 EP disclosed
WO-1995024383-A1 OXIME DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-14 WO disclosed