Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 17/20 | 0.76 |
| ▸ | EDNRB | P24530 | 16/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817417 | 0.92 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL7817358 | 0.89 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL6452207 | 0.86 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7538026 | 0.86 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6452202 | 0.86 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7942493 | 0.83 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL7810966 | 0.80 | EDNRB (0.75) | EDNRAEDNRB | |
| SCHEMBL8202426 | 0.80 | EDNRA (0.87) | EDNRAEDNRB | |
| SCHEMBL7809551 | 0.79 | EDNRA (0.63) | EDNRAEDNRBMAPT | |
| SCHEMBL8202186 | 0.79 | EDNRB (0.86) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612244-B1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2001-09-19 | — | — | EP | claimed |