SCHEMBL7804333

SCHEMBL7804333

Cc1cc(-n2cncn2)c2cccc(OCc3c(Cl)[c]ccc3Cl)c2n1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7856522 0.86 BDKRB2 (0.73) BDKRB2
SCHEMBL13145035 0.86 BDKRB2 (0.75) BDKRB2
SCHEMBL7806226 0.84 BDKRB2 (0.75) BDKRB2
SCHEMBL13145043 0.76 BDKRB2 (0.55) BDKRB2
SCHEMBL10365853 0.76 BDKRB2 (0.46) BDKRB2
SCHEMBL7086663 0.75 BDKRB2 (0.74) BDKRB2
SCHEMBL13145052 0.72 BDKRB2 (0.50) BDKRB2
SCHEMBL13145015 0.72 BDKRB2 (1.00) BDKRB2
SCHEMBL6938687 0.72 RORC (0.73) BDKRB2
SCHEMBL13145462 0.71 BDKRB2 (0.54) BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155013-A1 HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS FOURNIER INDUSTRIE ET SANTE (FR) 2001-11-21 EP disclosed
WO-2000050418-A1 HETEROCYCLIC BENZENESULPHONAMIDE COMPOUNDS AS BRADYKININE ANTAGONISTS FOURNIER INDUSTRIE ET SANTE (FR) 2000-08-31 WO disclosed