Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.59 |
| ▸ | CES1 | P23141 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151879 | 0.86 | CES2 (0.61) | CES2CES1L3MBTL1HTTKMT2A | |
| SCHEMBL9341491 | 0.85 | CES2 (0.59) | CES2CES1L3MBTL1HTTKMT2A | |
| SCHEMBL2097707 | 0.85 | CES2 (0.59) | CES2CES1L3MBTL1HTTKMT2A | |
| SCHEMBL1748151 | 0.84 | CES1 (0.63) | CES2CES1L3MBTL1HTTSNCA | |
| SCHEMBL30660847 | 0.81 | DGAT1 (0.58) | CES2CES1KMT2AGAANPC1 | |
| SCHEMBL10832422 | 0.81 | CES2 (0.59) | CES2CES1L3MBTL1HTTKMT2A | |
| SCHEMBL7606342 | 0.80 | CES2 (0.53) | CES2CES1L3MBTL1HTTKMT2A | |
| SCHEMBL6945689 | 0.80 | CES2 (0.53) | CES2CES1L3MBTL1HTTKMT2A | |
| SCHEMBL31280600 | 0.79 | SMN1; SMN2 (0.44) | CES2CES1HTTKMT2AGAA | |
| SCHEMBL9137806 | 0.78 | CES2 (0.55) | CES2CES1L3MBTL1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780380-B1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-6002028-A | FUNGICIDES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5986144-A | Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5945438-A | ANTIMYCOTIC AGENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0780380-A1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |