SCHEMBL7804371

SCHEMBL7804371

OC(c1ccc(C(O)(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl)cc1)(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
MAPK1 P28482 1/20 0.50
HIF1A Q16665 1/20 0.50
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
NR1H2 P55055 8/20 0.37
NR1H3 Q13133 8/20 0.37
MLYCD O95822 1/20 0.32
PGK1 P00558 2/20 0.32
PGK2 P07205 2/20 0.32
CYP19A1 P11511 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787416 0.85 TSHR (0.52) TSHRMAPK1HIF1ANR1H2NR1H3
SCHEMBL23149896 0.72 NR1H3 (0.50) TSHRNR1H2NR1H3MLYCD
SCHEMBL7804375 0.71 TSHR (0.48) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL8089046 0.69 TSHR (0.46) TSHRMAPK1HIF1AMEN1KMT2A
Dicofol SCHEMBL8376564 0.67 TSHR (1.00) TSHRMAPK1HIF1AMEN1KMT2A
Dicofol SCHEMBL9859511 0.67 TSHR (1.00) TSHRMAPK1HIF1AMEN1KMT2A
Dicofol SCHEMBL26640 0.67 TSHR (1.00) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL131990 0.67 NR1H2 (0.68) NR1H2NR1H3MLYCD
SCHEMBL6361861 0.65 TSHR (0.58) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL11100390 0.64 MAPK1 (0.65) TSHRMAPK1HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010008907-A1 FLUORINE-CONTAINING EPOXY RESIN COMPOSITION READILY SOLUBLE IN SOLVENT CANON KABUSHIKI KAISHA (JP) 2001-07-19 US disclosed
EP-0779337-A1 FLUORINE-CONTAINING EPOXY RESIN COMPOSITION HIGHLY SOLUBLE IN SOLVENTS CANON KABUSHIKI KAISHA (JP) 1997-06-18 EP disclosed