Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059043 | 0.79 | PGK1 (0.48) | TSHRMAPK1HIF1APGK1PGK2 | |
| SCHEMBL7804371 | 0.69 | TSHR (0.50) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL7804375 | 0.67 | TSHR (0.48) | TSHRMAPK1HIF1AMEN1KMT2A | |
| Dicofol SCHEMBL8376564 | 0.63 | TSHR (1.00) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL28383052 | 0.63 | — | — | |
| Dicofol SCHEMBL26640 | 0.63 | TSHR (1.00) | TSHRMAPK1HIF1AMEN1KMT2A | |
| Dicofol SCHEMBL9859511 | 0.63 | TSHR (1.00) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL11486977 | 0.61 | TSHR (0.61) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL423019 | 0.60 | — | — | |
| SCHEMBL23149882 | 0.60 | PTPN1 (0.48) | TSHRMAPK1HIF1APGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077928-A | Bis(dialkylmaleimide) derivative and polyetherimide for optical communications formed therefrom | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2000-06-20 | — | — | US | disclosed |