SCHEMBL7804375

SCHEMBL7804375

OC(Cl)(C(Cl)(Cl)Cl)C(Cl)(Cl)c1ccc(C(Cl)(Cl)C(O)(Cl)C(Cl)(Cl)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
MAPK1 P28482 1/20 0.48
HIF1A Q16665 1/20 0.48
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PGK1 P00558 2/20 0.31
PGK2 P07205 2/20 0.31
CYP19A1 P11511 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787419 0.86 TSHR (0.50) TSHRMAPK1HIF1APGK1PGK2
SCHEMBL7804371 0.71 TSHR (0.50) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL7784486 0.71 TSHR (0.33) TSHRMAPK1HIF1A
SCHEMBL11486979 0.67 TSHR (0.58) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL8089046 0.67 TSHR (0.46) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL18242501 0.66 TSHR (0.34) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL18242169 0.65 TSHR (0.33) TSHRMAPK1HIF1A
SCHEMBL11123925 0.65 MAPT (0.44) TSHRMAPK1HIF1AMEN1KMT2A
Dicofol SCHEMBL8376564 0.65 TSHR (1.00) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL18243502 0.65 TSHR (0.33) TSHRMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010008907-A1 FLUORINE-CONTAINING EPOXY RESIN COMPOSITION READILY SOLUBLE IN SOLVENT CANON KABUSHIKI KAISHA (JP) 2001-07-19 US disclosed
EP-0779337-A1 FLUORINE-CONTAINING EPOXY RESIN COMPOSITION HIGHLY SOLUBLE IN SOLVENTS CANON KABUSHIKI KAISHA (JP) 1997-06-18 EP disclosed