Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 2/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813907 | 0.91 | BCL9 (0.49) | TLR9TLR8TLR7BCL9CTNNB1 | |
| SCHEMBL7811643 | 0.89 | BCL9 (0.52) | ALDH1A1BCL9CTNNB1GAAHTT | |
| SCHEMBL7814105 | 0.88 | BCL9 (0.54) | ALDH1A1TLR9TLR8TLR7BCL9 | |
| SCHEMBL7804213 | 0.85 | BCL9 (0.49) | ALDH1A1BCL9CTNNB1TDP1CYP2C9 | |
| SCHEMBL7811471 | 0.84 | PARP10 (0.51) | ALDH1A1BCL9CTNNB1LMNAKMT2A | |
| SCHEMBL7817327 | 0.84 | BCL9 (0.48) | BCL9CTNNB1TDP1GAAHTT | |
| SCHEMBL7813463 | 0.84 | BCL9 (0.48) | BCL9CTNNB1TDP1GAAHTT | |
| SCHEMBL7804520 | 0.84 | HSD11B1 (0.55) | ALDH1A1BCL9CTNNB1GAASLC9A1 | |
| SCHEMBL7814050 | 0.84 | MEN1 (0.52) | BCL9CTNNB1TDP1CYP2C9MAPK1 | |
| SCHEMBL7817387 | 0.84 | BCL9 (0.47) | BCL9CTNNB1GAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |