Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 9/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804213 | 0.92 | BCL9 (0.49) | BCL9CTNNB1PARP10PARP14HSD11B1 | |
| SCHEMBL7813907 | 0.92 | BCL9 (0.49) | BCL9CTNNB1PARP10PARP14HSD11B1 | |
| SCHEMBL7811471 | 0.91 | PARP10 (0.51) | BCL9CTNNB1PARP10PARP14HSD11B1 | |
| SCHEMBL7813463 | 0.91 | BCL9 (0.48) | BCL9CTNNB1PARP10PARP14HSD11B1 | |
| SCHEMBL7814050 | 0.91 | MEN1 (0.52) | BCL9CTNNB1PARP10PARP14HSD11B1 | |
| SCHEMBL7804520 | 0.91 | HSD11B1 (0.55) | BCL9CTNNB1PARP10PARP14HSD11B1 | |
| SCHEMBL7817327 | 0.91 | BCL9 (0.48) | BCL9CTNNB1PARP10PARP14HSD11B1 | |
| SCHEMBL7811632 | 0.90 | BCL9 (0.47) | BCL9CTNNB1PARP10PARP14HSD11B1 | |
| SCHEMBL7804377 | 0.89 | ALDH1A1 (0.46) | BCL9CTNNB1ALDH1A1LMNAKMT2A | |
| SCHEMBL7817387 | 0.89 | BCL9 (0.47) | BCL9CTNNB1PARP10PARP14HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |