Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804407 | 0.95 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2ADRD4 | |
| SCHEMBL7813945 | 0.89 | PTGDR2 (0.56) | NPC1RAB9AMEN1KMT2ADRD4 | |
| SCHEMBL7817809 | 0.84 | S1PR1 (0.53) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL9011162 | 0.83 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2ADRD4 | |
| SCHEMBL7811596 | 0.83 | NPC1 (0.51) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7804382 | 0.82 | MEN1 (0.67) | MEN1KMT2ALMNAPTGDR2 | |
| SCHEMBL7814370 | 0.82 | CNR2 (0.50) | MEN1KMT2ATSHRLMNAPOLB | |
| SCHEMBL7811440 | 0.81 | LMNA (0.57) | NPC1MEN1KMT2ATSHRLMNA | |
| SCHEMBL9010976 | 0.81 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2ADRD4 | |
| SCHEMBL7811675 | 0.80 | KMT2A (0.58) | NPC1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |