Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811616 | 0.95 | NPC1 (0.52) | NPC1RAB9APARP14PARP10DRD4 | |
| SCHEMBL7817809 | 0.90 | S1PR1 (0.53) | NPC1RAB9APARP14PARP10DRD4 | |
| SCHEMBL7817601 | 0.89 | NPC1 (0.54) | NPC1RAB9APARP14PARP10DRD4 | |
| SCHEMBL7813354 | 0.86 | CCR5 (0.51) | HRH3TSHR | |
| SCHEMBL7811526 | 0.85 | PARP10 (0.53) | NPC1RAB9APARP14PARP10LMNA | |
| SCHEMBL9011270 | 0.85 | DRD4 (0.59) | NPC1RAB9APARP14PARP10DRD4 | |
| SCHEMBL7810022 | 0.85 | NPC1 (0.54) | NPC1RAB9APARP14PARP10DRD4 | |
| SCHEMBL7804397 | 0.83 | NPC1 (0.52) | NPC1RAB9APARP10DRD4HRH3 | |
| SCHEMBL9011045 | 0.82 | DRD4 (0.58) | NPC1RAB9APARP14PARP10DRD4 | |
| SCHEMBL7810104 | 0.82 | LMNA (0.67) | NPC1RAB9APARP14PARP10HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |