Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817555 | 0.92 | SMN1; SMN2 (0.61) | SMN1; SMN2NPSR1USP2HSD17B10KMT2A | |
| SCHEMBL7817574 | 0.84 | LMNA (0.58) | SMN1; SMN2NPSR1USP2HSD17B10KMT2A | |
| SCHEMBL7811675 | 0.80 | KMT2A (0.58) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL7811440 | 0.79 | LMNA (0.57) | SMN1; SMN2NPSR1USP2HSD17B10KMT2A | |
| SCHEMBL7813964 | 0.79 | CA12 (0.45) | KMT2ADRD2LMNAALDH1A1HPGD | |
| SCHEMBL7817803 | 0.79 | MAPT (0.55) | SMN1; SMN2NPSR1KMT2AMEN1DRD2 | |
| SCHEMBL7810089 | 0.79 | MAPT (0.53) | SMN1; SMN2NPSR1USP2KMT2AMEN1 | |
| SCHEMBL7813995 | 0.78 | USP2 (0.60) | NPSR1USP2HSD17B10KMT2AMEN1 | |
| SCHEMBL7810164 | 0.77 | MEN1 (0.58) | SMN1; SMN2NPSR1USP2HSD17B10KMT2A | |
| SCHEMBL27298400 | 0.75 | GAA (0.65) | SMN1; SMN2NPSR1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |