Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | RBP4 | P02753 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813944 | 0.92 | MEN1 (0.61) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7810142 | 0.90 | POLB (0.60) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7810154 | 0.90 | MEN1 (0.60) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7814258 | 0.89 | TSHR (0.61) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7813588 | 0.89 | TSHR (0.58) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7810112 | 0.88 | MEN1 (0.64) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7811604 | 0.87 | SMN1; SMN2 (0.66) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7810093 | 0.87 | MEN1 (0.62) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7813768 | 0.82 | MEN1 (0.51) | MEN1KMT2ANPSR1LMNAPOLB | |
| SCHEMBL7811376 | 0.81 | RBP4 (0.53) | MEN1KMT2ANPSR1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |