Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.68 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798016 | 0.90 | CTSS (0.69) | CTSSCTSLCTSBCTSKKMT2A | |
| SCHEMBL7809642 | 0.84 | CTSS (0.69) | CTSSCTSLCTSBCTSKKMT2A | |
| SCHEMBL1139545 | 0.81 | CTSS (1.00) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1139058 | 0.80 | CTSS (0.77) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4740683 | 0.78 | CTSS (0.55) | CTSSKMT2AHTTAKR1C3 | |
| SCHEMBL7798496 | 0.77 | CTSS (0.55) | CTSSCTSLCTSBCTSKKMT2A | |
| SCHEMBL7806195 | 0.76 | CTSS (0.49) | CTSSCTSLCTSBCTSKKMT2A | |
| SCHEMBL7806295 | 0.76 | CTSS (0.54) | CTSSCTSLCTSBCTSKKMT2A | |
| SCHEMBL1139645 | 0.74 | CTSS (0.68) | CTSSCTSLCTSBCTSKHTT | |
| SCHEMBL3799114 | 0.74 | CTSS (0.68) | CTSSCTSLCTSBCTSKHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142650-A1 | NOVEL CYCLOPENTANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |