Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.69 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | WNT3 | P56703 | 1/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804457 | 0.84 | CTSS (0.68) | CTSSCTSLCTSBCTSKAKR1C3 | |
| SCHEMBL1139147 | 0.82 | CTSS (1.00) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7798496 | 0.75 | CTSS (0.55) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL3798016 | 0.74 | CTSS (0.69) | CTSSCTSLCTSBCTSKAKR1C3 | |
| SCHEMBL7806195 | 0.74 | CTSS (0.49) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL7806295 | 0.74 | CTSS (0.54) | CTSSCTSLCTSBCTSKMEN1 | |
| SCHEMBL1139645 | 0.72 | CTSS (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL3799114 | 0.72 | CTSS (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL27868136 | 0.72 | CTSS (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1139151 | 0.72 | CTSS (0.54) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142650-A1 | NOVEL CYCLOPENTANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |