Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804581 | 1.00 | KMT2A (0.45) | KMT2AL3MBTL1MEN1ALDH1A1CYP3A4 | |
| SCHEMBL7801131 | 0.87 | ALDH1A1 (0.49) | KMT2AL3MBTL1MEN1ALDH1A1CYP3A4 | |
| SCHEMBL7801127 | 0.87 | ALDH1A1 (0.49) | KMT2AL3MBTL1MEN1ALDH1A1CYP3A4 | |
| SCHEMBL7804550 | 0.85 | LMNA (0.42) | KMT2AL3MBTL1MEN1ALDH1A1TDP1 | |
| SCHEMBL7804547 | 0.85 | LMNA (0.42) | KMT2AL3MBTL1MEN1ALDH1A1TDP1 | |
| SCHEMBL7806056 | 0.85 | HPGD (0.43) | KMT2AL3MBTL1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL7806058 | 0.85 | HPGD (0.43) | KMT2AL3MBTL1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL7801805 | 0.84 | LMNA (0.39) | KMT2AL3MBTL1MEN1ALDH1A1TDP1 | |
| SCHEMBL7801802 | 0.84 | LMNA (0.39) | KMT2AL3MBTL1MEN1ALDH1A1TDP1 | |
| SCHEMBL7805468 | 0.84 | ABL1 (0.46) | KMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |