Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811365 | 0.91 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7813977 | 0.90 | S1PR1 (0.52) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7811466 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AMEN1PTGDR | |
| SCHEMBL9011160 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9011192 | 0.82 | MEN1 (0.51) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7814230 | 0.82 | PTPN7 (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2HTR1A | |
| SCHEMBL7813847 | 0.82 | PPARG (0.55) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9011037 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7817501 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL12376851 | 0.78 | GCGR (0.52) | ALDH1A1KMT2AMEN1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |