Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011037 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTAVPR1AMEN1 | |
| SCHEMBL9011192 | 0.89 | MEN1 (0.51) | ALDH1A1KDM4EMAPTAVPR1AMEN1 | |
| SCHEMBL7804666 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTAVPR1AMEN1 | |
| SCHEMBL9011263 | 0.83 | PTGDR (0.46) | ALDH1A1KDM4EAVPR1AMEN1KMT2A | |
| SCHEMBL7813977 | 0.82 | S1PR1 (0.52) | ALDH1A1KDM4EMAPTAVPR1AMEN1 | |
| SCHEMBL7811365 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7813847 | 0.78 | PPARG (0.55) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9011065 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTNR1H4AVPR1A | |
| SCHEMBL7811466 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTAVPR1AMEN1 | |
| SCHEMBL9010977 | 0.75 | CCR5 (0.57) | ALDH1A1KDM4ENR1H4AVPR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |