Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 8/20 | 0.64 |
| ▸ | RORC | P51449 | 12/20 | 0.63 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811061 | 0.96 | BDKRB2 (0.66) | BDKRB2RORCBDKRB1 | |
| SCHEMBL7818251 | 0.96 | BDKRB2 (0.66) | BDKRB2RORCBDKRB1 | |
| Hydrochloric Acid SCHEMBL8039026 | 0.95 | BDKRB2 (0.65) | BDKRB2RORCBDKRB1 | |
| SCHEMBL7805297 | 0.95 | BDKRB2 (0.65) | BDKRB2RORCBDKRB1 | |
| Hydrochloric Acid SCHEMBL7945809 | 0.95 | BDKRB2 (0.65) | BDKRB2RORCBDKRB1 | |
| Hydrochloric Acid SCHEMBL7954771 | 0.94 | BDKRB2 (0.64) | BDKRB2RORCBDKRB1 | |
| SCHEMBL7805546 | 0.93 | RORC (0.65) | BDKRB2RORCBDKRB1 | |
| SCHEMBL7815230 | 0.92 | BDKRB2 (0.67) | BDKRB2RORCBDKRB1 | |
| SCHEMBL7805674 | 0.92 | BDKRB2 (0.64) | BDKRB2RORCBDKRB1 | |
| SCHEMBL7815579 | 0.92 | BDKRB2 (0.65) | BDKRB2RORCBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874841-B1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | claimed |
| EP-0874841-B1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |
| US-6211181-B1 | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIALLERGENS, AND ANTIASTHMATICS | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-04-03 | — | — | US | disclosed |
| EP-0874841-A1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR B2 ANTAGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997024349-A1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-07-10 | — | — | WO | disclosed |