Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632435 | 0.74 | LMNA (0.43) | GPR35HSD17B10MAPTALDH1A1CA1 | |
| SCHEMBL9017957 | 0.72 | NPC1 (0.41) | MAPK1MAPTALDH1A1CA1CA2 | |
| SCHEMBL13281083 | 0.72 | HSD17B10 (0.48) | MAPK1GPR35HSD17B10MAPTALDH1A1 | |
| SCHEMBL5368690 | 0.70 | AKR1C1 (0.49) | MAPK1GPR35MAPTALDH1A1LMNA | |
| SCHEMBL9125609 | 0.69 | ALDH1A1 (0.43) | MAPK1GPR35HSD17B10MAPTALDH1A1 | |
| SCHEMBL5370966 | 0.69 | ALDH1A1 (0.40) | MAPK1GPR35HSD17B10MAPTALDH1A1 | |
| SCHEMBL30937695 | 0.68 | HSD17B10 (0.44) | MAPK1GPR35HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5369495 | 0.68 | AKR1C1 (0.46) | MAPK1GPR35HSD17B10MAPTALDH1A1 | |
| SCHEMBL28114646 | 0.68 | ALDH1A1 (0.44) | GPR35HSD17B10MAPTALDH1A1LMNA | |
| SCHEMBL30937544 | 0.68 | AKR1C1 (0.46) | MAPK1GPR35HSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604705-B1 | 4-Hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID CO (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0604705-A1 | 4-Hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID COMPANY (US) | 1994-07-06 | — | — | EP | claimed |
| US-5281726-A | 4-hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | claimed |
| JP-6199742-A | — | — | None | — | — | JP | disclosed |
| EP-0852224-B1 | Aryne intermediates towards the preparation of herbicidal sulfamoyl urea and a process for their preparation | AMERICAN CYANAMID CO (US) | 2001-10-31 | — | — | EP | disclosed |
| CN-1055678-C | 4-hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID CO (US) | 2000-08-23 | — | — | CN | disclosed |
| EP-0604705-B1 | 4-Hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID CO (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0604705-B1 | 4-Hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID CO (US) | 1996-10-09 | — | — | EP | disclosed |
| JP-H06199742-A | 4-HYDROXY-2'-NITROBUTYROPHENONE AND TETRAHYDRO-2-(O-NITROPHENYL)-2-FURANOL | AMERICAN CYANAMID CO | 1994-07-19 | — | — | JP | disclosed |
| EP-0604705-A1 | 4-Hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID COMPANY (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0604705-A1 | 4-Hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID COMPANY (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0604705-A1 | 4-Hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID COMPANY (US) | 1994-07-06 | — | — | EP | disclosed |
| US-5281726-A | 4-hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5281726-A | 4-hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5281726-A | 4-hydroxy-2'-nitrobutyrophenone and tetrahydro-2-(o-nitrophenyl)-2-furanol useful as intermediates in the preparation of a crop-selective herbicide | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |