Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.81 |
| ▸ | PPARG | P37231 | 7/20 | 0.81 |
| ▸ | PPARD | Q03181 | 7/20 | 0.81 |
| ▸ | PPARA | Q07869 | 7/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.81 |
| ▸ | TSHR | P16473 | 4/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | FABP4 | P15090 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | TLR2 | O60603 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.81 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.81 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | ESR1 | P03372 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanoic Acid SCHEMBL1682245 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL6559646 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL28534845 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL10489552 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL9748587 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL25269213 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL6567029 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL11054069 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL15603224 | 0.95 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL9368385 | 0.93 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036557-B1 | Preemulsion and its use for making hair dyes as well as a method for making hair dye emulsions | GOLDWELL GMBH (DE) | 2001-04-11 | — | — | EP | claimed |
| CN-112336699-A | Progesterone vaginal slow-release soft capsule and its preparation method | 南京科宁检测科技有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-105670739-A | Cast iron processing cutting fluid | 周紫阳 | 2016-06-15 | — | — | CN | disclosed |
| CN-104846668-A | Improved textile printing and dyeing color fixing agent | QINGDAO DONGCHANGRUI TEXTILE PRODUCT CO LTD | 2015-08-19 | — | — | CN | disclosed |
| CN-103705017-A | Anti-static damp-proof cabinet | CHANGSHU CATEC ELECTRONIC EQUIPMENT FACTORY | 2014-04-09 | — | — | CN | disclosed |
| CN-1660311-A | Adhibition agent of Chinese traditional medicine for treating impotence and producing method | DENG XIANAN (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1660308-A | Plaster of Chinese traditional medicine for treating prospermia and preparation method | DENG XIAOAN (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1660310-A | Plaster of Chinese traditional medicine for treating sleep disorder and preparation method | DENG XIAOAN (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1660309-A | Adhibition agent of Chinese traditional medicine for treating prostatic hyperplasia and producing method | DENG XIAOAN (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1304714-A | Health-care shampoo and its preparing process | BIOCHEMICAL INST TIANXING BIOL (CN) | 2001-07-25 | — | — | CN | disclosed |