Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170250 | 0.79 | NPSR1 (0.36) | DHFRIMPDH2 | |
| SCHEMBL15554431 | 0.79 | IMPDH2 (0.34) | DHFRIMPDH2 | |
| SCHEMBL9409111 | 0.76 | DHFR (0.33) | DHFR | |
| SCHEMBL4078236 | 0.69 | — | — | |
| SCHEMBL9147340 | 0.68 | — | — | |
| SCHEMBL5823143 | 0.66 | TLR8 (0.36) | DHFRIMPDH2 | |
| SCHEMBL29061386 | 0.65 | — | — | |
| SCHEMBL11221112 | 0.63 | CDK1 (0.31) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL11306419 | 0.63 | DHFR (0.42) | DHFRIMPDH2 | |
| SCHEMBL20488326 | 0.63 | TLR8 (0.34) | DHFRIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001097993-A | 5-ALKYL-2-THIOCYTOSINE NUCLEOSIDE, ITS SALT, AND ANTIVIRAL AGENT CONTAINING THE COMPOUND | TOAGOSEI CO LTD | 2001-04-10 | — | — | JP | disclosed |