Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25159685 | 0.72 | SLC6A2 (0.31) | SLC6A2SLC6A3 | |
| SCHEMBL14401546 | 0.71 | HRH1 (0.34) | SLC6A2SLC6A3HRH1SLC6A4GAA | |
| SCHEMBL7805579 | 0.69 | HRH1 (0.45) | SLC6A2SLC6A3HRH1SLC6A4GAA | |
| SCHEMBL3345179 | 0.68 | HRH1 (0.37) | SLC6A2SLC6A3HRH1SLC6A4CA4 | |
| SCHEMBL10546701 | 0.65 | SLC6A2 (0.47) | SLC6A2SLC6A3HRH1SLC6A4CA4 | |
| SCHEMBL14527576 | 0.63 | DDB1 (0.45) | SLC6A2SLC6A3HRH1SLC6A4GAA | |
| SCHEMBL10339339 | 0.62 | HRH1 (0.42) | SLC6A2SLC6A3HRH1SLC6A4CA4 | |
| SCHEMBL15850434 | 0.61 | LTA4H (0.38) | SLC6A2SLC6A3SLC6A4CA4RECQL | |
| SCHEMBL18727509 | 0.61 | SLC6A2 (0.35) | SLC6A2SLC6A3HRH1SLC6A4 | |
| SCHEMBL14627789 | 0.61 | HRH1 (0.34) | SLC6A2SLC6A3HRH1SLC6A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144303-A1 | 6-SUBSTITUTED PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | Array Biopharma, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |