Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1022337 | 0.87 | CHRNB2 (0.52) | CHRNB2CHRNA4CCNT1CDK9P2RY14 | |
| SCHEMBL1022339 | 0.87 | CHRNB2 (0.52) | CHRNB2CHRNA4CCNT1CDK9P2RY14 | |
| SCHEMBL7214962 | 0.81 | CHRNB2 (0.48) | CHRNB2CHRNA4CCNT1CDK9P2RY14 | |
| SCHEMBL6574854 | 0.81 | CHRNB2 (0.48) | CHRNB2CHRNA4P2RY14 | |
| SCHEMBL6214667 | 0.79 | CHRNB2 (0.55) | CHRNB2CHRNA4P2RY14 | |
| SCHEMBL12093045 | 0.78 | CHRNB2 (0.67) | CHRNB2CHRNA4CCNT1CDK9P2RY14 | |
| Cadaverine Tartrate SCHEMBL1023378 | 0.77 | CHRNB2 (0.43) | CHRNB2CHRNA4P2RY14 | |
| SCHEMBL6573882 | 0.76 | CHRNB2 (0.43) | CHRNB2CHRNA4CCNT1CDK9P2RY14 | |
| SCHEMBL1267308 | 0.74 | CCNT1 (0.48) | CHRNB2CHRNA4CCNT1CDK9 | |
| SCHEMBL2417457 | 0.74 | CHRNB2 (0.42) | CHRNB2CHRNA4CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068204-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND USE OF 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 2001-01-17 | — | — | EP | claimed |
| WO-1999038866-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED FORM AND USE OF 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 1999-08-05 | — | — | WO | claimed |
| EP-1068204-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND USE OF 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999038866-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED FORM AND USE OF 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 1999-08-05 | — | — | WO | disclosed |