Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.33 |
| ▸ | CDK9 | P50750 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805901 | 0.81 | CHRNB2 (0.54) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL6574854 | 0.77 | CHRNB2 (0.48) | CHRNB2CHRNA4P2RY14 | |
| SCHEMBL7809874 | 0.75 | CHRNB2 (0.55) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL6993886 | 0.75 | CHRNB2 (0.55) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL12093045 | 0.75 | CHRNB2 (0.67) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL2881954 | 0.75 | CHRNB2 (0.67) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL18689619 | 0.73 | CHRNB2 (0.65) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL1022337 | 0.72 | CHRNB2 (0.52) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| SCHEMBL1023489 | 0.71 | CHRNB2 (0.54) | CHRNB2CHRNA4P2RY14CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL1025419 | 0.70 | CHRNB2 (0.52) | CHRNB2CHRNA4P2RY14CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149095-A1 | NOVEL AZABICYCLO DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2001-10-31 | — | — | EP | claimed |
| WO-2000044746-A1 | NOVEL AZABICYCLO DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2000-08-03 | — | — | WO | claimed |
| US-6617459-B2 | 8-azabicyclo(3.2.1)oct-2-ene and 9-azabicyclo(3.3.1)non-2-ene derivatives; monoamine neurotransmitter and serotonine reuptake inhibitors; radionuclide-labeled derivatives for diagnosis and detection | NEUROSEARCH A/S (DK) | 2003-09-09 | — | — | US | disclosed |
| EP-1149095-A1 | NOVEL AZABICYCLO DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044746-A1 | NOVEL AZABICYCLO DERIVATIVES AND THEIR USE | NEUROSEARCH A/S (DK) | 2000-08-03 | — | — | WO | disclosed |