SCHEMBL780607

SCHEMBL780607

CC(C)(C)c1ccc2c(-c3ccc(-n4c5ccc(-c6cccc7c6sc6ccccc67)cc5c5cc(-c6cccc7c6sc6ccccc67)ccc54)cc3)c3ccccc3c(-c3ccccc3)c2c1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
PRKDC P78527 2/20 0.36
PPARG P37231 3/20 0.34
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
PPARA Q07869 1/20 0.33
SERPINE1 P05121 1/20 0.32
PARP14 Q460N5 1/20 0.32
PMM2 O15305 1/20 0.31
MPI P34949 1/20 0.31
PHOSPHO1 Q8TCT1 1/20 0.31
DNMT1 P26358 3/20 0.31
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780756 0.98 ALOX5 (0.41) ALOX5PRKDCPPARGTNKSTNKS2
SCHEMBL780714 0.98 ALOX5 (0.41) ALOX5PRKDCPPARGTNKSTNKS2
SCHEMBL781120 0.98 ALOX5 (0.44) ALOX5PRKDCPPARGTNKSTNKS2
SCHEMBL781051 0.91 ALOX5 (0.45) ALOX5PRKDCPPARGTNKSTNKS2
SCHEMBL10165717 0.91 ALOX5 (0.48) ALOX5PRKDCPPARGTNKSTNKS2
SCHEMBL780882 0.90 ALOX5 (0.42) ALOX5PRKDCPPARGTNKSTNKS2
SCHEMBL780911 0.90 ALOX5 (0.47) ALOX5PRKDCTNKSTNKS2PARP14
SCHEMBL769504 0.90 ALOX5 (0.51) ALOX5PRKDCTNKSTNKS2PARP14
SCHEMBL780982 0.89 ALOX5 (0.48) ALOX5PRKDCTNKSTNKS2PARP14
SCHEMBL10443464 0.89 ALOX5 (0.48) ALOX5PRKDCTNKSTNKS2PARP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-12-29 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160380211-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PRKDC 3567/4885PPARG 1283/4885
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PRKDC 3567/4885PPARG 1283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.