Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405660 | 0.95 | KCNH2 (0.44) | KCNH2MEN1KMT2AMAOBNPC1 | |
| SCHEMBL438993 | 0.95 | KCNH2 (0.44) | KCNH2MEN1KMT2AMAOBNPC1 | |
| SCHEMBL14598859 | 0.95 | KCNH2 (0.44) | KCNH2MEN1KMT2AMAOBNPC1 | |
| SCHEMBL9136144 | 0.85 | KCNH2 (0.49) | KCNH2MEN1KMT2AMAOBNPC1 | |
| Trifluoroacetic Acid SCHEMBL7803888 | 0.85 | ITGB1 (0.33) | MAOBNPC1RAB9A | |
| SCHEMBL10494760 | 0.82 | KCNH2 (0.49) | KCNH2MEN1KMT2AMAOBNPC1 | |
| SCHEMBL438991 | 0.80 | MEN1 (0.43) | KCNH2MEN1KMT2AMAOBNPC1 | |
| SCHEMBL438992 | 0.80 | MEN1 (0.43) | KCNH2MEN1KMT2AMAOBNPC1 | |
| SCHEMBL7804379 | 0.80 | NR1D1 (0.50) | MEN1KMT2AMAOBNPC1TP53 | |
| SCHEMBL6527472 | 0.80 | KCNH2 (0.47) | KCNH2MEN1KMT2AMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207858-B1 | ELIMINATES THE NEED FOR ION EXCHANGE CHROMOTOGRAPHIC SEPARATION OF INTERMEDIATES, USEFUL AS BI-FUNCTIONAL CHELATORS IN RADIOIMMUNOTHERAPY AND IMAGING, DIETHYLENETRIAMINEPENTAACETIC ACID (DTPA), SUITABLE FOR | IDEC PHARMACEUTICALS CORPORATION | 2001-03-27 | — | — | US | claimed |
| US-6207858-B1 | ELIMINATES THE NEED FOR ION EXCHANGE CHROMOTOGRAPHIC SEPARATION OF INTERMEDIATES, USEFUL AS BI-FUNCTIONAL CHELATORS IN RADIOIMMUNOTHERAPY AND IMAGING, DIETHYLENETRIAMINEPENTAACETIC ACID (DTPA), SUITABLE FOR | IDEC PHARMACEUTICALS CORPORATION | 2001-03-27 | — | — | US | disclosed |