Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | AHCY | P23526 | 5/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646292 | 0.82 | BCHE (0.56) | BCHEADORA1AHCYDPP4MEN1 | |
| SCHEMBL13150889 | 0.82 | ADORA3 (0.57) | BCHEADORA1AHCYDPP4MEN1 | |
| SCHEMBL11402107 | 0.82 | AHCY (0.58) | BCHEADORA1AHCYDOT1LNT5E | |
| SCHEMBL11416201 | 0.81 | BCHE (0.58) | BCHEADORA1AHCYDPP4MEN1 | |
| SCHEMBL29056308 | 0.81 | BCHE (0.56) | BCHEADORA1AHCYDPP4MEN1 | |
| SCHEMBL23619450 | 0.81 | BCHE (0.56) | BCHEADORA1AHCYDPP4MEN1 | |
| SCHEMBL23619452 | 0.81 | BCHE (0.58) | BCHEADORA1AHCYDPP4MEN1 | |
| SCHEMBL31484190 | 0.81 | ADORA1 (0.59) | BCHEADORA1AHCYDPP4NT5E | |
| SCHEMBL23982337 | 0.80 | ADORA3 (0.57) | BCHEADORA1AHCYDPP4MEN1 | |
| Cordycepin SCHEMBL22081032 | 0.80 | ADORA3 (0.63) | ADORA1AHCYDPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716856-B1 | Therapeutic uses of 2',5'-oligoadenylate derivatives | UNIV TEMPLE (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-0420872-B1 | THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES | UNIV TEMPLE (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0716856-A2 | Therapeutic uses of 2',5'-oligoadenylate derivatives | Temple University of the Commonwealth System of Higher Education (US) | 1996-06-19 | — | — | EP | disclosed |