Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14911977 | 0.85 | PDE10A (0.45) | CCR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3710009 | 0.81 | PARP1 (0.54) | CCR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9018899 | 0.81 | PDE10A (0.44) | CCR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL6196701 | 0.81 | CCR1 (0.63) | CCR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5301328 | 0.79 | CCR1 (1.00) | CCR1LMNAPDE10APARP1CYSLTR1 | |
| SCHEMBL9220073 | 0.78 | CCR1 (0.65) | CCR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL12844021 | 0.78 | PDE10A (0.48) | CCR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31434366 | 0.78 | PARP1 (0.48) | CCR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL8588461 | 0.77 | CCR1 (0.63) | CCR1ALDH1A1PDE10APARP1KDM4E | |
| SCHEMBL28722027 | 0.77 | CCR1 (0.63) | CCR1LMNAKMT2AMEN1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |