SCHEMBL7806715

SCHEMBL7806715

[CH2]CC(=O)CCCCCCCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.60
MAPT P10636 1/20 0.60
CES2 O00748 4/20 0.56
CES1 P23141 4/20 0.56
GPR84 Q9NQS5 7/20 0.54
PPARG P37231 7/20 0.54
PPARD Q03181 7/20 0.54
PPARA Q07869 7/20 0.54
HDAC11 Q96DB2 5/20 0.54
TSHR P16473 4/20 0.54
PTPN1 P18031 3/20 0.54
ALDH1A1 P00352 2/20 0.54
TLR2 O60603 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
FABP4 P15090 2/20 0.54
SLC22A6 Q4U2R8 1/20 0.54
SLC22A8 Q8TCC7 1/20 0.54
MEN1 O00255 1/20 0.54
ESR1 P03372 1/20 0.54
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9189691 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL27721086 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL7808386 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL7808122 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL4452914 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL1898399 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL17078443 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL9459408 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL6467976 1.00 KMT2A (0.60) KMT2AMAPTCES2CES1GPR84
SCHEMBL28633257 0.98 KMT2A (0.64) KMT2AMAPTCES2CES1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024017358-A1 MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF 贝达药业股份有限公司 2024-01-25 WO claimed
WO-2024017358-A1 MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF 贝达药业股份有限公司 2024-01-25 WO disclosed
CN-104628711-B Preparation method of diglycerol diacetal 太原理工大学 2017-02-22 CN disclosed
CN-104628711-A Preparation method of diglycerol diacetal UNIV TAIYUAN TECHNOLOGY 2015-05-20 CN disclosed
EP-0685478-B1 QUINOLINE DERIVATIVES UBE INDUSTRIES (JP) 2001-10-24 EP disclosed
US-5591752-A LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE UBE INDUSTRIES, LTD. (JP) 1997-01-07 US disclosed
EP-0685478-A1 QUINOLINE DERIVATIVE UBE INDUSTRIES, LTD. (JP) 1995-12-06 EP disclosed