Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189691 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL27721086 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL7808386 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL7808122 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL4452914 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL7806715 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL1898399 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL17078443 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL9459408 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL28633257 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| CN-108368265-A | Thiadiazoles and pyridine polymers, its synthesis and application thereof | 默克专利股份有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105658761-B | Conjugated polymer | 默克专利股份有限公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-107922369-A | Compound for optical activity device | 默克专利股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107915661-A | Organic semiconductor compound | 默克专利股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107636040-A | Thiadiazolopyridine Polymers, Their Synthesis And Their Use | 默克专利股份有限公司 | 2018-01-26 | — | — | CN | disclosed |
| EP-3172214-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-05-31 | — | — | EP | disclosed |
| CN-106661058-A | Extended nonlinear acene derivatives and their use as organic semiconductors | 默克专利股份有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106536528-A | Polycyclic polymers based on tetra-heteroaryl indacenodithiophenes and their use | 默克专利股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| WO-2016015598-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |
| EP-0885875-A1 | VINYLENE COMPOUNDS AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0872484-A1 | ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1998-10-21 | — | — | EP | disclosed |
| CN-1195352-A | Organosilicon compounds, liquid-crystal composition, and liquid-crystal display element | CHISSO CORP (JP) | 1998-10-07 | — | — | CN | disclosed |
| US-5770108-A | HIGH SPEED RESPONSE, MOLECULAR ORIENTATION, HIGH CONTRAST, RECEPTIVITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0751133-A1 | Pyrimidine compound, and liquid crystal composition and liquid crystal element using the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |
| US-4590291-A | Thrombin inhibitory new dihydroxybenzene ether derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-20 | — | — | US | disclosed |
| EP-0068250-A1 | Dioxybenzene ether derivatives, pharmaceutical compositions containing them, process for the preparation thereof and their use | BAYER AG (DE) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | IL4, ARG2, CASP4 | KMT2A 3219/4885MAPT 1906/4885CES2 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.