Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189691 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL27721086 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL7808122 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL4452914 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL7806715 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL1898399 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL17078443 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL9459408 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL6467976 | 1.00 | KMT2A (0.60) | KMT2AMAPTCES2CES1GPR84 | |
| SCHEMBL28633257 | 0.98 | KMT2A (0.64) | KMT2AMAPTCES2CES1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209664-A1 | BICYCLIC HETEROARYL AMINE COMPOUNDS AS PI3K INHIBITORS | Bristol-Myers Squibb Company (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| CN-1202103-A | Excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 1998-12-16 | — | — | CN | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |
| EP-0074598-B1 | SYNTHETIC RESIN COMPOSITIONS CONTAINING 2,2,6,6-TETRAMETHYL PIPERIDINYL TRIAZINES | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1986-11-12 | — | — | EP | disclosed |
| US-4415689-A | PHOTOSTABILIZERS | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0074598-A2 | Synthetic resin compositions containing 2,2,6,6-tetramethyl piperidinyl triazines | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1983-03-23 | — | — | EP | disclosed |