SCHEMBL7806791

SCHEMBL7806791

Fc1cc(OC(F)(F)F)nc(F)n1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
GMNN O75496 1/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
GAA P10253 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
ALOX15 P16050 1/20 0.32
NFKB1 P19838 1/20 0.32
SLC6A2 P23975 1/20 0.32
SCN4A P35499 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SLC6A3 Q01959 1/20 0.32
PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7804843 0.83
SCHEMBL7804832 0.81
SCHEMBL7806796 0.79 KMT2A (0.45) NPC1RAB9AGMNNUSP2LMNA
SCHEMBL7804841 0.79 POLB (0.35) NPC1RAB9AGMNNUSP2LMNA
SCHEMBL7937932 0.76 CHRNA7 (0.35) SCN9A
SCHEMBL7806788 0.73 LMNA (0.39) NPC1RAB9ALMNACYP1A2CYP2C9
SCHEMBL9586211 0.70 NPC1 (0.31) NPC1RAB9AGMNNUSP2LMNA
SCHEMBL113096 0.69
SCHEMBL9196255 0.68 PGK1 (0.34) NPC1RAB9AGMNNUSP2LMNA
SCHEMBL9194396 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445644-B1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF AG (DE) 1995-05-24 EP claimed
US-5237063-A TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-08-17 US claimed
EP-0445644-A1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF Aktiengesellschaft (DE) 1991-09-11 EP claimed
US-6235904-B1 VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. BASF AKTIENGESELLSCHAFT (DE) 2001-05-22 US disclosed
EP-0572429-B1 SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF BASF AG (DE) 2001-04-18 EP disclosed
US-5591694-A COMPOUND USED TO CONTROL UNDESIRABLE PLANT GROWTH BASF AKTIENGESELLSCHAFT (DE) 1997-01-07 US disclosed
EP-0446743-B1 Herbicidal sulfonylureas, process for their preparation and intermediates BASF AG (DE) 1995-08-02 EP disclosed
US-5434124-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1995-07-18 US disclosed
EP-0445642-B1 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation BASF AG (DE) 1995-07-12 EP disclosed
EP-0445644-B1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF AG (DE) 1995-05-24 EP disclosed
EP-0600967-B1 HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME BASF AG (DE) 1995-04-19 EP disclosed
US-5283332-A 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof BASF AKTIENGESELLSCHAFT (DE) 1994-02-01 US disclosed
US-5276007-A Herbicidal sulfonylureas BASF AKTIENGESELLSCHAFT (DE) 1994-01-04 US disclosed
EP-0572429-A1 SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF BASF Aktiengesellschaft (DE) 1993-12-08 EP disclosed
US-5237063-A TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed
WO-1993005048-A2 HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME BASF AKTIENGESELLSCHAFT (DE) 1993-03-18 WO disclosed
WO-1992014715-A1 SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1992-09-03 WO disclosed
EP-0446743-A2 Herbicidal sulfonylureas, process for their preparation and intermediates BASF Aktiengesellschaft (DE) 1991-09-18 EP disclosed
EP-0445642-A1 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation BASF Aktiengesellschaft (DE) 1991-09-11 EP disclosed
EP-0445644-A1 Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation BASF Aktiengesellschaft (DE) 1991-09-11 EP disclosed