Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808132 | 0.83 | ALOX5 (0.63) | CYSLTR1ALOX5FFAR1AKR1B1 | |
| SCHEMBL7807149 | 0.81 | FFAR1 (0.68) | CYSLTR1ALOX5FFAR1AKR1B1GPBAR1 | |
| SCHEMBL9505352 | 0.80 | ALOX5 (0.85) | CYSLTR1ALOX5FFAR1AKR1B1GPBAR1 | |
| SCHEMBL7813785 | 0.79 | CYSLTR1 (0.88) | CYSLTR1FFAR1AKR1B1 | |
| SCHEMBL9505341 | 0.79 | ALOX5 (0.62) | CYSLTR1ALOX5FFAR1AKR1B1 | |
| SCHEMBL10512475 | 0.78 | PDE10A (0.77) | CYSLTR1GPBAR1 | |
| SCHEMBL8735648 | 0.78 | CYSLTR1 (0.78) | CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL7801881 | 0.78 | CYSLTR1 (0.64) | CYSLTR1ALOX5FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8814429 | 0.78 | CYSLTR1 (0.65) | CYSLTR1 | |
| SCHEMBL7008427 | 0.77 | GPBAR1 (0.64) | CYSLTR1ALOX5FFAR1AKR1B1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775133-B1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2001-05-30 | — | — | EP | disclosed |
| EP-0775133-A1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004267-A1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |