Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.85 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692276 | 0.92 | ALOX5 (1.00) | ALOX5CYSLTR1GPBAR1 | |
| SCHEMBL10692490 | 0.92 | ALOX5 (1.00) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL7807149 | 0.86 | FFAR1 (0.68) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL7808132 | 0.85 | ALOX5 (0.63) | ALOX5CYSLTR1FFAR1AKR1B1 | |
| SCHEMBL9428833 | 0.85 | ALOX5 (0.74) | ALOX5CYSLTR1FFAR1AKR1B1PDE10A | |
| SCHEMBL9505341 | 0.83 | ALOX5 (0.62) | ALOX5CYSLTR1FFAR1AKR1B1 | |
| SCHEMBL9593916 | 0.81 | ALOX5 (0.59) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL9504046 | 0.80 | ALOX5 (0.58) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL7806985 | 0.80 | CYSLTR1 (0.60) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL9507030 | 0.79 | ALOX5 (0.64) | ALOX5CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250693-A | Lipoxygenase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-05 | — | — | US | claimed |
| EP-0547148-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | claimed |
| US-5250693-A | Lipoxygenase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-05 | — | — | US | disclosed |