SCHEMBL7807028

SCHEMBL7807028

CS(=O)(=O)c1ccc(/C(=C2\CCOC2=O)c2ccc(F)c(F)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 17/20 0.47
PTGS1 P23219 6/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7807030 1.00 PTGS2 (0.47) PTGS2PTGS1
SCHEMBL7814075 0.92 PTGS2 (0.39) PTGS2PTGS1
SCHEMBL7814078 0.92 PTGS2 (0.39) PTGS2PTGS1
SCHEMBL7808799 0.90 PTGS2 (0.46) PTGS2PTGS1
SCHEMBL7808801 0.90 PTGS2 (0.46) PTGS2PTGS1
SCHEMBL7807292 0.87 PTGS2 (0.48) PTGS2PTGS1
SCHEMBL7807293 0.87 PTGS2 (0.48) PTGS2PTGS1
SCHEMBL7807269 0.87 PTGS2 (0.48) PTGS2PTGS1
SCHEMBL7810541 0.87 PTGS2 (0.47) PTGS2PTGS1
SCHEMBL7810537 0.87 PTGS2 (0.47) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0891345-B1 NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF UNION PHARMA SCIENT APPL (FR) 2001-08-16 EP disclosed
US-6180651-B1 ANTIINFLAMMATORY AGENTS; ANALGESICS BRISTOL-MYERS SQUIBB 2001-01-30 US disclosed