Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366184 | 0.91 | HTT (0.52) | TXNRD1SMN1; SMN2LMNAPOLBGLA | |
| SCHEMBL9762459 | 0.91 | TXNRD1 (0.51) | TXNRD1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL9622912 | 0.79 | TXNRD1 (0.55) | TXNRD1SMN1; SMN2LMNAMAPTTP53 | |
| SCHEMBL6651527 | 0.77 | SMN1; SMN2 (0.56) | TXNRD1SMN1; SMN2LMNAMAPTTP53 | |
| SCHEMBL18063513 | 0.76 | KMT2A (0.60) | TXNRD1SMN1; SMN2POLBMAPTGLA | |
| SCHEMBL1720601 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAMAPTTP53GLA | |
| SCHEMBL10975489 | 0.73 | POLB (0.58) | SMN1; SMN2LMNAPOLBMAPTTSHR | |
| SCHEMBL26288630 | 0.72 | KMT2A (0.47) | TXNRD1SMN1; SMN2POLBMAPTTSHR | |
| SCHEMBL6651523 | 0.71 | SMN1; SMN2 (0.51) | TXNRD1SMN1; SMN2LMNAMAPTTP53 | |
| SCHEMBL30215796 | 0.70 | PDE2A (0.71) | SMN1; SMN2TSHRHTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6056797-A | — | — | None | — | — | JP | disclosed |
| EP-0802193-B1 | Process for the preparation of substituted pyrimidines | LONZA AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| US-5840892-A | Process for the preparation of substituted pyrimidines | LONZA AG (CH) | 1998-11-24 | — | — | US | disclosed |
| EP-0802193-A1 | Process for the preparation of substituted pyrimidines | LONZA AG (CH) | 1997-10-22 | — | — | EP | disclosed |
| JP-H0656797-A | OPTICALLY ACTIVE PYRIMIDINYL-OR TRIAZINYL-OXY (OR-THIO) CARBOXYLIC ACID DERIVATIVE, ITS PRODUCTION AND ITS USE AS HERBICIDE OR PLANT GROWTH REGULATOR | HOECHST AG | 1994-03-01 | — | — | JP | disclosed |
| EP-0562510-A1 | Optically active pyrimidinyl- or triazinyl-oxy-(or -thio)-carbonic acid derivatives, processes for their production and their use as herbicides or plant growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |