Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807155 | 0.91 | TXNRD1 (0.52) | HTTSMN1; SMN2TSHRNPSR1MCOLN3 | |
| SCHEMBL9762459 | 0.86 | TXNRD1 (0.51) | SMN1; SMN2TSHRNPSR1KMT2ATXNRD1 | |
| SCHEMBL18063513 | 0.85 | KMT2A (0.60) | HTTSMN1; SMN2TSHRNPSR1MCOLN3 | |
| SCHEMBL9622912 | 0.74 | TXNRD1 (0.55) | HTTSMN1; SMN2TSHRNPSR1KMT2A | |
| SCHEMBL6561352 | 0.73 | SMN1; SMN2 (0.78) | HTTSMN1; SMN2TSHRNPSR1MCOLN3 | |
| SCHEMBL10975489 | 0.72 | POLB (0.58) | HTTSMN1; SMN2TSHRNPSR1KMT2A | |
| SCHEMBL19214329 | 0.72 | KMT2A (0.46) | HTTSMN1; SMN2TSHRNPSR1KMT2A | |
| SCHEMBL8558105 | 0.71 | ALDH1A1 (0.48) | HTTSMN1; SMN2TSHRNPSR1KMT2A | |
| SCHEMBL31527791 | 0.70 | SMN1; SMN2 (0.52) | HTTSMN1; SMN2TSHRNPSR1MCOLN3 | |
| SCHEMBL6651527 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRTXNRD1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223406-B1 | PYRIMIDINE DERIVATIVES AND HERBICIDAL USES THEREOF | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4770691-A | HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| EP-0223406-A1 | Pyrimidine derivatives and herbicidal uses thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |