Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809136 | 0.98 | ALOX5 (0.66) | ALOX5GRM5 | |
| SCHEMBL7811098 | 0.96 | ALOX5 (0.68) | ALOX5GRM5 | |
| SCHEMBL7815083 | 0.92 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL8409170 | 0.88 | ALOX5 (0.65) | ALOX5GRM5 | |
| SCHEMBL8409097 | 0.87 | ALOX5 (0.64) | ALOX5GRM5 | |
| SCHEMBL7802752 | 0.87 | ALOX5 (0.85) | ALOX5GRM5 | |
| SCHEMBL8408893 | 0.86 | ALOX5 (0.65) | ALOX5GRM5 | |
| SCHEMBL7802468 | 0.86 | ALOX5 (0.84) | ALOX5GRM5 | |
| SCHEMBL8413029 | 0.84 | ALOX5 (0.67) | ALOX5GRM5 | |
| SCHEMBL2436940 | 0.79 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784054-B1 | 1,2,3,4-TETRAHYDROQUINOXALINEDIONE DERIVATIVES AND USE AS GLUTAMATE RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMA CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| EP-0787127-B1 | 5-LIPOXYGENASE INHIBITORS | PFIZER (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6096743-A | 1,2,3,4-tetrahydroquinoxalinedione derivative | YAMANOUCHI PHARMACEUTICALS CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-6063928-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, CARDIOTONIC AGENTS | PFIZER INC (US) | 2000-05-16 | — | — | US | disclosed |
| EP-0784054-A1 | 1,2,3,4-TETRAHYDROQUINOXALINEDIONE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-16 | — | — | EP | disclosed |