Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409170 | 0.99 | ALOX5 (0.65) | ALOX5CYP3A4CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL8408893 | 0.97 | ALOX5 (0.65) | ALOX5CYP3A4CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL8413029 | 0.95 | ALOX5 (0.67) | ALOX5CYP3A4CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL7807384 | 0.87 | ALOX5 (0.66) | ALOX5GRM5 | |
| SCHEMBL7802468 | 0.87 | ALOX5 (0.84) | ALOX5CYP3A4CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL7802752 | 0.86 | ALOX5 (0.85) | ALOX5CYP3A4CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL7809136 | 0.85 | ALOX5 (0.66) | ALOX5GRM5 | |
| SCHEMBL7811098 | 0.83 | ALOX5 (0.68) | ALOX5GRM5 | |
| SCHEMBL7815083 | 0.79 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL2436940 | 0.78 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883106-A | 5-lipoxygenase inhibitors | PFIZER INC. (US) | 1999-03-16 | — | — | US | disclosed |