Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 10/20 | 0.44 |
| ▸ | ACACA | Q13085 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142591 | 0.86 | KDM4E (0.52) | KDM4EMEN1KMT2APOLBRAB9A | |
| SCHEMBL3693246 | 0.83 | OPRM1 (0.64) | OPRM1OPRD1OPRK1 | |
| SCHEMBL6178262 | 0.81 | KDM4E (0.59) | KDM4EMEN1KMT2APOLBRAB9A | |
| SCHEMBL9267594 | 0.80 | LMNA (0.63) | RAB9A | |
| SCHEMBL2310157 | 0.80 | KDM4E (0.51) | KDM4EMEN1KMT2APOLBRAB9A | |
| SCHEMBL2310168 | 0.80 | KDM4E (0.51) | KDM4EMEN1KMT2APOLBRAB9A | |
| SCHEMBL4790595 | 0.79 | OPRM1 (0.55) | KDM4EMEN1KMT2APOLBRAB9A | |
| SCHEMBL15643190 | 0.79 | KDM4E (0.65) | KDM4EMEN1KMT2APOLBRAB9A | |
| SCHEMBL7810467 | 0.78 | KDM4E (0.59) | KDM4EMEN1KMT2APOLBRAB9A | |
| SCHEMBL7810519 | 0.78 | KDM4E (0.59) | KDM4EMEN1KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066261-A1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048871-A1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-30 | — | — | WO | disclosed |