SCHEMBL7807633

SCHEMBL7807633

CNc1cc(CC(O)CO)cc(-c2cccn2C)c1N

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.31
GSK3B P49841 2/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7800924 0.83 ADRA1D (0.31)
SCHEMBL7456583 0.79 PRKCA (0.31) PRKCAGSK3B
SCHEMBL7807682 0.79
SCHEMBL7812217 0.77 ADRA1D (0.31)
SCHEMBL8100365 0.76 PCSK9 (0.31)
SCHEMBL7808839 0.75 PTPN1 (0.36) CYP3A4
SCHEMBL7812294 0.75
SCHEMBL7456352 0.75
SCHEMBL7461302 0.73 MEN1 (0.34)
SCHEMBL7454371 0.73 CSNK2A1 (0.33) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed