Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 9/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807480 | 0.88 | NPC1 (0.39) | HDAC2HDAC1NPC1RAB9AATM | |
| SCHEMBL7805999 | 0.84 | TDP1 (0.43) | HDAC2HDAC1NPC1RAB9AATM | |
| SCHEMBL7808585 | 0.79 | KCNH2 (0.46) | HDAC2HDAC1NPC1RAB9AATM | |
| SCHEMBL7806018 | 0.77 | HDAC1 (0.38) | HDAC2HDAC1NPC1RAB9AATM | |
| SCHEMBL7462791 | 0.77 | KCNH2 (0.38) | KCNH2MAPTSLC6A9TDO2DPP4 | |
| SCHEMBL7807635 | 0.75 | HDAC2 (0.36) | HDAC2HDAC1NPC1RAB9AATM | |
| SCHEMBL7800810 | 0.74 | GBA1 (0.36) | HDAC1MAPTKDM4EHPGDHDAC6 | |
| SCHEMBL7808518 | 0.74 | CYP3A4 (0.33) | DPP4 | |
| SCHEMBL7812212 | 0.74 | CFTR (0.32) | LMNADPP4ALDH1A1 | |
| SCHEMBL10420297 | 0.73 | S100B (0.50) | DPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |