SCHEMBL7807706

SCHEMBL7807706

Cn1cccc1C1=CC(N)(Cl)C=CC1N

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PCSK9 Q8NBP7 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP2A6 P11509 1/20 0.30
CYP2A13 Q16696 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8105779 0.84 PCSK9 (0.32) PCSK9ALDH1A1CYP2A6CYP2A13
SCHEMBL7800675 0.76
SCHEMBL7808544 0.76
SCHEMBL8099410 0.71
SCHEMBL7456771 0.67
SCHEMBL7460980 0.65 CHRM2 (0.34)
SCHEMBL7456213 0.64 CHRM2 (0.33) CYP2A6
SCHEMBL197196 0.62 PCSK9 (0.60) PCSK9ALDH1A1CYP2A6CYP2A13
SCHEMBL8100357 0.61
SCHEMBL8099970 0.60 KDM4E (0.32) PCSK9ALDH1A1CYP2A6CYP2A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed