Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807706 | 0.84 | PCSK9 (0.31) | PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL8100357 | 0.75 | — | — | |
| SCHEMBL8099410 | 0.75 | — | — | |
| SCHEMBL7808544 | 0.72 | — | — | |
| SCHEMBL197196 | 0.63 | PCSK9 (0.60) | PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL7808479 | 0.58 | KDM4E (0.33) | PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL6816479 | 0.57 | PCSK9 (0.34) | PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL26310838 | 0.56 | ALDH1A1 (0.39) | PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL6444709 | 0.55 | PCSK9 (0.73) | PCSK9ALDH1A1CYP2A6CYP2A13 | |
| SCHEMBL3188837 | 0.54 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |