Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818192 | 0.84 | PTGS1 (0.62) | KMT2AADRB1ADRA1AMIFHTR2A | |
| SCHEMBL7806911 | 0.84 | PTGS1 (0.62) | KMT2AADRB1ADRA1AMIFHTR2A | |
| SCHEMBL15990183 | 0.83 | ADRB1 (0.56) | KMT2AADRB1ADRA1AMIFHTR2A | |
| SCHEMBL4366704 | 0.83 | ADRB1 (0.50) | KMT2AADRB1ADRA1AMIFHTR2A | |
| SCHEMBL1578725 | 0.82 | KMT2A (0.81) | KMT2ALMNAPTGS1PTGS2TSHR | |
| SCHEMBL5522307 | 0.82 | KMT2A (0.81) | KMT2ALMNAPTGS1PTGS2TSHR | |
| SCHEMBL5514748 | 0.82 | KMT2A (0.81) | KMT2ALMNAPTGS1PTGS2TSHR | |
| SCHEMBL24260675 | 0.81 | ADRB1 (0.45) | KMT2AADRB1ADRA1AMIFHTR2A | |
| SCHEMBL31570147 | 0.81 | KMT2A (0.53) | KMT2APTGS1PTGS2TSHRRAB9A | |
| SCHEMBL26684921 | 0.81 | KMT2A (0.53) | KMT2APTGS1PTGS2TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |