SCHEMBL4366704

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3895480	0.89	KMT2A (0.52)	LMNAKMT2ATSHRPTGS1PTGS2
	SCHEMBL7807735	0.83	KMT2A (0.55)	ADRB1ADRA1AMIFHTR2AHTR2B
	SCHEMBL8909021	0.82	ADRB1 (0.46)	ADRB1ADRA1AMIFHTR2AHTR2B
	SCHEMBL17764345	0.81	KMT2A (0.44)	KMT2ATSHRRAB9AGAAPTGS1
	SCHEMBL22807046	0.81	HDAC4 (0.50)	LMNAKDM4EKMT2AGAAALDH1A1
	SCHEMBL3652623	0.81	KMT2A (0.44)	KMT2ATSHRRAB9AGAAPTGS1
	SCHEMBL30456687	0.81	KMT2A (0.44)	KMT2ATSHRRAB9AGAAPTGS1
	SCHEMBL14032279	0.81	L3MBTL1 (0.55)	POLBALDH1A1
	SCHEMBL30264834	0.81	KMT2A (0.48)	KMT2ARAB9AMEN1
	SCHEMBL29440604	0.81	HDAC4 (0.50)	LMNAKDM4EKMT2AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.