Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.53 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397422 | 0.82 | CFTR (0.59) | — | |
| SCHEMBL7974378 | 0.81 | JAK3 (0.73) | NTRK1KITPIK3C3RIPK1IGF1R | |
| SCHEMBL22044083 | 0.80 | BACE1 (0.71) | NTRK1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3768119 | 0.78 | RIPK1 (0.81) | NTRK1KITRIPK1IGF1R | |
| SCHEMBL14384821 | 0.77 | POLB (0.59) | BRD4NQO2KMT2AMEN1KDM4E | |
| SCHEMBL5750386 | 0.77 | MEN1 (0.43) | BRD4NQO2KMT2AMEN1KDM4E | |
| SCHEMBL24900046 | 0.76 | PIK3C3 (0.55) | BRD4NTRK1NQO2KMT2AMEN1 | |
| SCHEMBL7779477 | 0.76 | KMT2A (0.59) | KMT2AMEN1KDM4ESMN1; SMN2POLB | |
| SCHEMBL9087412 | 0.76 | PRKCB (0.62) | KITIGF1R | |
| SCHEMBL9086100 | 0.76 | PRKCB (0.62) | KMT2AKDM4EKITMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953872-B1 | Photographic element containing improved acylacetamido yellow dye-forming coupler | EASTMAN KODAK CO (US) | 2001-08-22 | — | — | EP | disclosed |
| US-5998107-A | TRIAZINE DERIVATIVE OF A 3-INDOLOACETANILIDE | EASTMAN KODAK COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0953872-A1 | Photographic element containing improved acylacetamido yellow dye-forming coupler | EASTMAN KODAK COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |