Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803219 | 0.76 | CYP11B2 (0.64) | NR4A2TTKCYP2A6CYP2E1CYP2C9 | |
| SCHEMBL21753339 | 0.74 | TTK (0.51) | TTKCYP2A6CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL22159339 | 0.72 | SCN9A (0.51) | GSK3BSCN9ACYP2A6CYP3A4BRD4 | |
| SCHEMBL4241393 | 0.72 | CYP11B2 (0.56) | TTKCYP11B1CYP11B2 | |
| SCHEMBL3931286 | 0.71 | TTK (0.49) | TTKCYP2A6CYP2E1CYP2C9CYP2B6 | |
| SCHEMBL3933850 | 0.70 | ERN1 (0.56) | TTKERN1CYP3A4ALDH1A1CYP11B1 | |
| SCHEMBL23242341 | 0.70 | CYP2A6 (0.50) | CYP2A6ALDH1A1 | |
| SCHEMBL24296515 | 0.69 | NR4A2 (0.76) | NR4A2S1PR1S1PR3BRD4CYP11B1 | |
| SCHEMBL20914819 | 0.69 | SCN9A (0.78) | SCN9ACYP2C9CYP2B6CYP2C19 | |
| SCHEMBL18003572 | 0.68 | PRMT5 (0.47) | GSK3BDYRK1AELANEBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |